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Stomatologija 2022; 24 (4): 100-3 195 KB

Association between apical periodontitis and root canal treatment in patients with type II diabetes. A systematic review

Karolina Budreikaitė¹, Mariam Varoneckaitė¹, Danielė Oleinikaitė¹, Juozas Žilinskas²

Summary

Background. Type II diabetes mellitus (T2DM) is a chronic endocrine disease affecting over 6% of the world population. Sustained hyperglycaemia plays a role in inhibited healing and chronic inflammation which can lead to complications after root canal treatment, such as delayed healing of apical periodontitis.

Material and methods. The systematic review adhered to PRISMA guidelines and databases of PubMed, ScienceDirect, and The Cochrane library were used to perform the search. The search was carried out between November 15 and November 30 in the year 2021. Aim. To evaluate the relationship between apical periodontitis and root canal treatment in patients with type II diabetes.

Results. Primary database search yielded 313 results. After checking the content and relevance of the articles, 4 articles were used with a total of 15810 patients. Out of 4 studies, 3 concluded that apical periodontitis after root canal treatment was statistically significantly more frequent in patients with T2DM than in control groups. However, the results from another study showed that there is no significant correlation between T2DM and post-treatment apical periodontitis (p>0.05).

Conclusions. A statistically significant relationship was found between T2DM patients and the occurrence of apical periodontitis in most studies.

Key words: diabetes, apical periodontitis, root canal treatment, endodontics.

Received: 22 02 2022

Accepted for publishing: 27 12 2022

¹Faculty of Odontology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania

²Department of Prosthodontics, Faculty of odontology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania

Address correspondence to Karolina Budreikaitė, Faculty of Odontology, Medical Academy, Lithuanian University of Health Sciences, Eivenių g. 2, LT-50161, Kaunas, Lithuania.

E-mail address: karolinabudreikaite28@gmail.com



	Baltic Dental and Maxillofacial Journal

2022, Vol. 24, No. 4 CONTENTS REVIEW Surgical treatment methods of medication-related osteonecrosis of the jaw. A systematic review Jonas Zigmantavičius, Gerda Kilinskaitė, Ričardas Kubilius 91-99 Association between apical periodontitis and root canal treatment in patients with type II diabetes. A systematic review Karolina Budreikaitė, Mariam Varoneckaitė, Danielė Oleinikaitė, Juozas Žilinskas 100-103 Second generation platelet concentrates in periodontal surgery: A narrative review and clinical perspectives Emilija Migauskaitė, Jūratė Žekonienė, Arūnas Rimkevičius, Giedrius Krukonis 104-111 Prevalence of peri-implantitis and peri-mucositis in pristine and augmented bone in periodontally compromised patients. A literature review Nomeda Basevičienė, Austė Bendoraitytė-Antipovienė, Ugnė Mikelionytė 112-124 © 2023 Stomatologija		Stomatologija 2022; 24 (4): 100-3 195 KB Association between apical periodontitis and root canal treatment in patients with type II diabetes. A systematic review Karolina Budreikaitė¹, Mariam Varoneckaitė¹, Danielė Oleinikaitė¹, Juozas Žilinskas² Summary Background. Type II diabetes mellitus (T2DM) is a chronic endocrine disease affecting over 6% of the world population. Sustained hyperglycaemia plays a role in inhibited healing and chronic inflammation which can lead to complications after root canal treatment, such as delayed healing of apical periodontitis. Material and methods. The systematic review adhered to PRISMA guidelines and databases of PubMed, ScienceDirect, and The Cochrane library were used to perform the search. The search was carried out between November 15 and November 30 in the year 2021. Aim. To evaluate the relationship between apical periodontitis and root canal treatment in patients with type II diabetes. Results. Primary database search yielded 313 results. After checking the content and relevance of the articles, 4 articles were used with a total of 15810 patients. Out of 4 studies, 3 concluded that apical periodontitis after root canal treatment was statistically significantly more frequent in patients with T2DM than in control groups. However, the results from another study showed that there is no significant correlation between T2DM and post-treatment apical periodontitis (p>0.05). Conclusions. A statistically significant relationship was found between T2DM patients and the occurrence of apical periodontitis in most studies. Key words: diabetes, apical periodontitis, root canal treatment, endodontics. Received: 22 02 2022 Accepted for publishing: 27 12 2022 ¹Faculty of Odontology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania ²Department of Prosthodontics, Faculty of odontology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania Address correspondence to Karolina Budreikaitė, Faculty of Odontology, Medical Academy, Lithuanian University of Health Sciences, Eivenių g. 2, LT-50161, Kaunas, Lithuania. E-mail address: karolinabudreikaite28@gmail.com