Baltic Dental and Maxillofacial Journal
Main page Back issues Editorial board Information
2023, Vol. 25, No. 3



Multiple-tooth autotransplantation patients: Long-term (4–8 years) results of treatment
Janne Tiigimäe-Saar


Odontogenic sinusitis: causes, symptoms and treatment. A review of current literature and concepts
Žygimantas Petronis, Audra Janovskienė, Ričardas Kubilius, Juozas Žilinskas, Marijus Leketas


Cytological diagnosis of Langerhans cell histiocytosis. Apropos 2 cases
Eleni Thodou, Konstantina Papaharalambous, Eleni Lappa, Irini Skliva, Ekaterini Diamanti, Giannis Kokkinakis, Eleni Konsolaki, Dimitrios Tamiolakis

Intraoral surgical treatment of large complex odontoma with technology support in planning
Renato Torres Augusto Neto, Júlio César Silva de Oliveira, Luiz Henrique Soares Torres, Deborah Laurindo Pereira Santos, Marisa Aparecida Cabrini Gabrielli, Valfrido Antônio Pereira Filho


© 2024 Stomatologija

Stomatologija 2023; 25 (3): 78-83 344 KB

Cytological diagnosis of Langerhans cell histiocytosis. Apropos 2 cases

Eleni Thodou1, Konstantina Papaharalambous2, Eleni Lappa3, Irini Skliva3, Ekaterini Diamanti3, Giannis Kokkinakis3, Eleni Konsolaki4, Dimitrios Tamiolakis3


Langerhans cell histiocytosis (LCH) comprises a wide spectrum of clinical presentations in children and adults, ranging from favorable lesions to aggressive disseminated disease. We present 2 cases where cytology introduced the diagnosis of LCH in the appropriate clinicoradioliogical settings. Cytology can serve accurately in LCH interpretation based on the characteristic cytomorphology and selected immunocytochemistry, so unwarranted biopsy can be overruled and treatment can be adjusted largely where histopathology services are unavailable. Diagnosis may be difficult in cases with scant or insufficient cellular material.

Key words: Langerhans cell histiocytosis, cytology, histopathology, langerin, CD1a, S-100.

Received: 28 03 2023

Accepted for publishing: 25 09 2023

1Department of Pathology, Faculty of Medicine University of Thessaly, Greece

2Department of Pathology, IASO Thessalias, Greece

3Departments of Pathology, Faculty of Medicine, University of Crete, Greece

4Department of Maxillofacial Surgery, University Hospital of Heraklion, Crete, Greece

Address correspondence to Dimitrios Tamiolakis, Department of Pathology-Cytopathology, University Hospital of Heraklion, Voutes, Heraklion, Crete, Greece.

E-mail address: